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Mapping quantitative traits with random and with ascertained sibships
Use of a robust score statistic based on a variance components model to map quantitative trait loci in randomly sampled pedigrees is reviewed. Sibships ascertained through a single proband are discussed. Under a standard assumption of multivariate normality, two suggested methods of ascertainment co...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419519/ https://ncbi.nlm.nih.gov/pubmed/15084737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401713101 |
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