Leukocyte engagement of fibrin(ogen) via the integrin receptor α(M)β(2)/Mac-1 is critical for host inflammatory response in vivo

The leukocyte integrin α(M)β(2)/Mac-1 appears to support the inflammatory response through multiple ligands, but local engagement of fibrin(ogen) may be particularly important for leukocyte function. To define the biological significance of fibrin(ogen)-α(M)β(2) interaction in vivo, gene-targeted mi...

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Bibliografiske detaljer
Main Authors: Flick, Matthew J., Du, XinLi, Witte, David P., Jiroušková, Markéta, Soloviev, Dmitry A., Busuttil, Steven J., Plow, Edward F., Degen, Jay L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC419487/
https://ncbi.nlm.nih.gov/pubmed/15173886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420741
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