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Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin α(M)β(2) binding motif
Fibrin deposition within joints is a prominent feature of arthritis, but the precise contribution of fibrin(ogen) to inflammatory events that cause debilitating joint damage remains unknown. To determine the importance of fibrin(ogen) in arthritis, gene-targeted mice either deficient in fibrinogen (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000806/ https://ncbi.nlm.nih.gov/pubmed/17932565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30134 |
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