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Mismatch cleavage by single-strand specific nucleases

We have investigated the ability of single-strand specific (sss) nucleases from different sources to cleave single base pair mismatches in heteroduplex DNA templates used for mutation and single-nucleotide polymorphism analysis. The TILLING (Targeting Induced Local Lesions IN Genomes) mismatch cleav...

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Bibliographic Details
Main Authors: Till, Bradley J., Burtner, Chris, Comai, Luca, Henikoff, Steven
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC419476/
https://ncbi.nlm.nih.gov/pubmed/15141034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh599
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