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Discovery of the widespread site-specific single-stranded nuclease family Ssn

Abstract Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. We identify and characterize one such family, from the GIY-YIG superfamily, of widely distributed site-specific si...

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Bibliografski detalji
Glavni autori: Martin Chenal, Alex Rivera-Millot, Luke B. Harrison, Ahmed S. Khairalla, Cecilia Nieves, Ève Bernet, Mansoore Esmaili, Manel Belkhir, Jonathan Perreault, Frédéric J. Veyrier
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-03-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-025-57514-1
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