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NMR structure of the DNA decamer duplex containing double T·G mismatches of cis–syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC–hHR23B complex

The cis–syn cyclobutane pyrimidine dimer (CPD) is a cytotoxic, mutagenic and carcinogenic DNA photoproduct and is repaired by the nucleotide excision repair (NER) pathway in mammalian cells. The XPC–hHR23B complex as the initiator of global genomic NER binds to sites of certain kinds of DNA damage....

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Dettagli Bibliografici
Autori principali: Lee, Joon-Hwa, Park, Chin-Ju, Shin, Jae-Sun, Ikegami, Takahisa, Akutsu, Hideo, Choi, Byong-Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC419456/
https://ncbi.nlm.nih.gov/pubmed/15121904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh568
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