NMR structure of the DNA decamer duplex containing double T·G mismatches of cis–syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC–hHR23B complex

The cis–syn cyclobutane pyrimidine dimer (CPD) is a cytotoxic, mutagenic and carcinogenic DNA photoproduct and is repaired by the nucleotide excision repair (NER) pathway in mammalian cells. The XPC–hHR23B complex as the initiator of global genomic NER binds to sites of certain kinds of DNA damage....

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Lee, Joon-Hwa, Park, Chin-Ju, Shin, Jae-Sun, Ikegami, Takahisa, Akutsu, Hideo, Choi, Byong-Seok
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2004
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh568
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