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XRCC1–DNA polymerase β interaction is required for efficient base excision repair

X-ray repair cross-complementing protein-1 (XRCC1)-deficient cells are sensitive to DNA damaging agents and have delayed processing of DNA base lesions. In support of its role in base excision repair, it was found that XRCC1 forms a tight complex with DNA ligase IIIα and also interacts with DNA poly...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Dianova, Irina I., Sleeth, Kate M., Allinson, Sarah L., Parsons, Jason L., Breslin, Claire, Caldecott, Keith W., Dianov, Grigory L.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15141024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh567
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