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XRCC1–DNA polymerase β interaction is required for efficient base excision repair

X-ray repair cross-complementing protein-1 (XRCC1)-deficient cells are sensitive to DNA damaging agents and have delayed processing of DNA base lesions. In support of its role in base excision repair, it was found that XRCC1 forms a tight complex with DNA ligase IIIα and also interacts with DNA poly...

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Detalhes bibliográficos
Main Authors: Dianova, Irina I., Sleeth, Kate M., Allinson, Sarah L., Parsons, Jason L., Breslin, Claire, Caldecott, Keith W., Dianov, Grigory L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419455/
https://ncbi.nlm.nih.gov/pubmed/15141024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh567
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