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ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1
Approximately 25% of childhood B-cell precursor acute lymphoblastic leukemia have an ETV6/RUNX1 (E/R) gene fusion that results from a t(12;21). This genetic subgroup of leukemia is associated with near-triploidy, near-tetraploidy, and trisomy 21 as rather specific types of secondary changes. Here, w...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194424/ https://ncbi.nlm.nih.gov/pubmed/20190817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.53 |
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