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Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard Soulier Syndrome

BACKGROUND: Bernard Soulier Syndrome (BSS) is an inherited bleeding disorder characterized by macrothrombocytopenia. Platelet transfusion is used for the management of bleeding but repeated transfusion often results in allo-immunization. We have recently shown phenotypic correction of murine BSS (GP...

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Библиографические подробности
Главные авторы: Kanaji, Sachiko, Fahs, Scot A., Ware, Jerry, Montgomery, Robert R., Shi, Qizhen
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194147/
https://ncbi.nlm.nih.gov/pubmed/25066812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12673
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