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Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells()

Plasmacytoid dendritic cells (pDC) produce type I interferon (IFN-I) in response to viruses and are routinely identified in mice by SiglecH expression. SiglecH is a sialic acid-binding immunoglobulin-like lectin that has an immunomodulatory role during viral infections. Here, we evaluated the impact...

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Detalhes bibliográficos
Main Authors: Swiecki, Melissa, Wang, Yaming, Riboldi, Elena, Kim, Alfred H.J., Dzutsev, Amiran, Gilfillan, Susan, Vermi, William, Ruedl, Christiane, Trinchieri, Giorgio, Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194082/
https://ncbi.nlm.nih.gov/pubmed/24683186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303135
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