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Plasmacytoid Dendritic Cells Contribute to Systemic but Not Local Antiviral Responses to HSV Infections

Plasmacytoid dendritic cells (pDC) produce type I interferons (IFN-I) and proinflammatory cytokines in response to viruses; however, their contribution to antiviral immunity in vivo is unclear. In this study, we investigated the impact of pDC depletion on local and systemic antiviral responses to he...

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Detalhes bibliográficos
Main Authors: Swiecki, Melissa, Wang, Yaming, Gilfillan, Susan, Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812046/
https://ncbi.nlm.nih.gov/pubmed/24204273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003728
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