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Plasmacytoid Dendritic Cell Ablation Impacts Early Interferon Responses and Antiviral NK and CD8(+) T Cell Accrual

Plasmacytoid dendritic cells (pDCs) mediate type I interferon (IFN-I) responses to viruses that are recognized through the Toll-like receptor 7 (TLR7) or TLR9 signaling pathway. However, it is unclear how pDCs regulate the antiviral responses via innate and adaptive immune cells. We generated diphth...

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Bibliografische gegevens
Hoofdauteurs: Swiecki, Melissa, Gilfillan, Susan, Vermi, William, Wang, Yaming, Colonna, Marco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588567/
https://ncbi.nlm.nih.gov/pubmed/21130004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.11.020
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