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GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

Elongation factor G (EF-G) promotes the movement of two tRNAs and the mRNA through the ribosome in each cycle of peptide elongation. During translocation, the tRNAs transiently occupy intermediate positions on both small (30S) and large (50S) ribosomal subunits. How EF-G and GTP hydrolysis control t...

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Autors principals: Holtkamp, Wolf, Cunha, Carlos E, Peske, Frank, Konevega, Andrey L, Wintermeyer, Wolfgang, Rodnina, Marina V
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193938/
https://ncbi.nlm.nih.gov/pubmed/24614227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387465
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