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Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates

The Mus81-Eme1 complex is a structure-selective endonuclease with a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, or double-strand breaks. To explain the molecular basis of 3′ flap substrate recognition and...

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Detalhes bibliográficos
Main Authors: Gwon, Gwang Hyeon, Jo, Aera, Baek, Kyuwon, Jin, Kyeong Sik, Fu, Yaoyao, Lee, Jong-Bong, Kim, YoungChang, Cho, Yunje
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193937/
https://ncbi.nlm.nih.gov/pubmed/24733841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201487820
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