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eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining
eIF5B is a eukaryal translational GTPase that catalyzes ribosomal subunit joining to form elongation-competent ribosomes. Despite its central role in protein synthesis, the mechanistic details that govern the function of eIF5B or its archaeal and bacterial (IF2) orthologs remained unclear. Here, we...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193923/ https://ncbi.nlm.nih.gov/pubmed/24686316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387344 |
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