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Mechanism of eIF6 release from the nascent 60S ribosomal subunit

SBDS protein (deficient in the inherited leukemia-predisposition disorder Shwachman-Diamond syndrome) and the GTPase EFL1 (an EF-G homolog) activate nascent 60S ribosomal subunits for translation by catalyzing eviction of the antiassociation factor eIF6 from nascent 60S ribosomal subunits. However,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Struct Mol Biol
Egile Nagusiak: Weis, Félix, Giudice, Emmanuel, Churcher, Mark, Jin, Li, Hilcenko, Christine, Wong, Chi C, Traynor, David, Kay, Robert R, Warren, Alan J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871238/
https://ncbi.nlm.nih.gov/pubmed/26479198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3112
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