Compound prioritization methods increase rates of chemical probe discovery in model organisms

Pre-selection of compounds that are more likely to induce a phenotype can increase the efficiency and reduce the costs for model organism screening. To identify such molecules, we screened ~81,000 compounds in S. cerevisiae and identified ~7,500 that inhibit cell growth. Screening these growth-inhib...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wallace, Iain M, Urbanus, Malene L, Luciani, Genna M, Burns, Andrew R, Han, Mitchell KL, Wang, Hao, Arora, Kriti, Heisler, Lawrence E, Proctor, Michael, St. Onge, Robert P, Roemer, Terry, Roy, Peter J, Cummins, Carolyn L, Bader, Gary D, Nislow, Corey, Giaever, Guri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193902/
https://ncbi.nlm.nih.gov/pubmed/22035796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.018
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak