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Asymmetric gold-catalyzed lactonizations in water at room temperature()

Asymmetric gold-catalyzed hydrocarboxylations are reported that show broad substrate scope. The hydrophobic effect associated with in situ-formed aqueous nanomicelles leads to good-to-excellent ee’s of product lactones. In-flask product isolation, along with recycling of the catalyst and reaction me...

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Autores principales: Handa, Sachin, Lippincott, Daniel J., Slack, Eric D., Aue, Donald H., Lipshutz, Bruce H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193796/
https://ncbi.nlm.nih.gov/pubmed/25124085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404729
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