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Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol

A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach allows many modes of reactivity, which can be used to access various analogs of saxitoxin.

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Bibliografiske detaljer
Main Authors: Pearson, Aaron D., Williams, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192658/
https://ncbi.nlm.nih.gov/pubmed/25313264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.08.058
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