Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer

BACKGROUND: In this study we investigated the in vitro and in vivo anticancer effect of carnosol, a naturally occurring polyphenol, in triple negative breast cancer. RESULTS: We found that carnosol significantly inhibited the viability and colony growth induced G2 arrest in the triple negative MDA-M...

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Detalhes bibliográficos
Main Authors: Al Dhaheri, Yusra, Attoub, Samir, Ramadan, Gaber, Arafat, Kholoud, Bajbouj, Khuloud, Karuvantevida, Noushad, AbuQamar, Synan, Eid, Ali, Iratni, Rabah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192122/
https://ncbi.nlm.nih.gov/pubmed/25299698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109630
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