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AAV Delivery of TNF-α shRNA Attenuates Cold-induced Pulmonary Hypertension and Pulmonary Arterial Remodeling
Cold temperatures are associated with increased mortality and morbidity of cardiovascular and pulmonary disease. Cold exposure causes lung inflammation, pulmonary hypertension (PH) and right ventricle (RV) hypertrophy, but there is no effective therapy due to unknown mechanism. Here we investigated...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192064/ https://ncbi.nlm.nih.gov/pubmed/25185133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03791 |
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