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Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

Background. While inflammation predicts mortality in treated human immunodeficiency virus (HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell markers remains unclear. Methods. We assessed immunologic predictors of mortality in a case-control study within the...

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Bibliografiske detaljer
Main Authors: Hunt, Peter W., Sinclair, Elizabeth, Rodriguez, Benigno, Shive, Carey, Clagett, Brian, Funderburg, Nicholas, Robinson, Janet, Huang, Yong, Epling, Lorrie, Martin, Jeffrey N., Deeks, Steven G., Meinert, Curtis L., Van Natta, Mark L., Jabs, Douglas A., Lederman, Michael M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192038/
https://ncbi.nlm.nih.gov/pubmed/24755434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu238
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