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QM/MM Molecular Dynamics Study of the Galactopyranose → Galactofuranose Reaction Catalysed by Trypanosoma cruzi UDP-Galactopyranose Mutase

The enzyme UDP-Galactopyranose Mutase (UGM) catalyses the conversion of galactopyranose into galactofuranose. It is known to be critical for the survival and proliferation of several pathogenic agents, both prokaryotic and eukaryotic. Among them is Trypanosoma cruzi, the parasite responsible for Cha...

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Detalles Bibliográficos
Main Authors: Pierdominici-Sottile, Gustavo, Cossio Pérez, Rodrigo, Galindo, Johan F., Palma, Juliana
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192007/
https://ncbi.nlm.nih.gov/pubmed/25299056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109559
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