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QM/MM Molecular Dynamics Study of the Galactopyranose → Galactofuranose Reaction Catalysed by Trypanosoma cruzi UDP-Galactopyranose Mutase

The enzyme UDP-Galactopyranose Mutase (UGM) catalyses the conversion of galactopyranose into galactofuranose. It is known to be critical for the survival and proliferation of several pathogenic agents, both prokaryotic and eukaryotic. Among them is Trypanosoma cruzi, the parasite responsible for Cha...

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Autors principals: Pierdominici-Sottile, Gustavo, Cossio Pérez, Rodrigo, Galindo, Johan F., Palma, Juliana
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192007/
https://ncbi.nlm.nih.gov/pubmed/25299056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109559
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