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MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation and a Neoplastic State
The MYC oncogene regulates gene expression through multiple mechanisms and its overexpression culminates in tumorigenesis. MYC inactivation reverses turmorigenesis through the loss of hallmark features of cancer including autonomous proliferation and survival. Here we report that MYC via miR-17-92 m...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191901/ https://ncbi.nlm.nih.gov/pubmed/25117713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.06.014 |
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