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FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response
Human single-strand (ss) DNA binding proteins 1 (hSSB1) has been shown to participate in DNA damage response and maintenance of genome stability by regulating the initiation of ATM-dependent signaling. ATM phosphorylates hSSB1 and prevents hSSB1 from ubiquitin-proteasome-mediated degradation. Howeve...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191430/ https://ncbi.nlm.nih.gov/pubmed/25249620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku876 |
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