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Sequence-Dependent Biophysical Modeling of DNA Amplification
A theoretical framework for prediction of the dynamic evolution of chemical species in DNA amplification reactions, for any specified sequence and operating conditions, is reported. Using the polymerase chain reaction (PCR) as an example, we developed a sequence- and temperature-dependent kinetic mo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190609/ https://ncbi.nlm.nih.gov/pubmed/25296327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.019 |
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