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Sequence-Dependent Biophysical Modeling of DNA Amplification

A theoretical framework for prediction of the dynamic evolution of chemical species in DNA amplification reactions, for any specified sequence and operating conditions, is reported. Using the polymerase chain reaction (PCR) as an example, we developed a sequence- and temperature-dependent kinetic mo...

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Hlavní autoři: Marimuthu, Karthikeyan, Jing, Chaoran, Chakrabarti, Raj
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190609/
https://ncbi.nlm.nih.gov/pubmed/25296327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.019
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