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Protein Unfolding by Biological Unfoldases: Insights from Modeling
The molecular determinants of the high efficiency of biological machines like unfoldases (e.g., the proteasome) are not well understood. We propose a model to study protein translocation into the chamber of biological unfoldases represented as a funnel. It is argued that translocation is a much fast...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190598/ https://ncbi.nlm.nih.gov/pubmed/25296319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.035 |
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