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Use of single stranded targeting DNA or negative selection does not further increase the efficiency of a GGTA1 promoter trap
Although several techniques have been developed to create gene knockouts in pigs, homologous recombination will continue to be required for site-specific genome modifications that are more sophisticated than gene disruption (base changes, domain exchanges, conditional knockouts). The objective of th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190589/ https://ncbi.nlm.nih.gov/pubmed/25309937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2325-9787.1000101 |
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