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Phosphodiesterase 8a Supports HIV-1 Replication in Macrophages at the Level of Reverse Transcription

BACKGROUND: HIV-1 infected macrophages play a key role in HIV-1 infection. Even during anti-retroviral treatment, macrophages keep producing virus due to suboptimal tissue penetration and reduced efficacy of antiretrovirals. It is therefore of major importance to understand which host factors are in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Booiman, Thijs, Cobos Jiménez, Viviana, van Dort, Karel A., van 't Wout, Angélique B., Kootstra, Neeltje A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190361/
https://ncbi.nlm.nih.gov/pubmed/25295610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109673
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