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Phosphodiesterase 8a Supports HIV-1 Replication in Macrophages at the Level of Reverse Transcription

BACKGROUND: HIV-1 infected macrophages play a key role in HIV-1 infection. Even during anti-retroviral treatment, macrophages keep producing virus due to suboptimal tissue penetration and reduced efficacy of antiretrovirals. It is therefore of major importance to understand which host factors are in...

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Main Authors: Booiman, Thijs, Cobos Jiménez, Viviana, van Dort, Karel A., van 't Wout, Angélique B., Kootstra, Neeltje A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190361/
https://ncbi.nlm.nih.gov/pubmed/25295610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109673
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