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Biosynthesis of Taxadiene in Saccharomyces cerevisiae : Selection of Geranylgeranyl Diphosphate Synthase Directed by a Computer-Aided Docking Strategy

Identification of efficient key enzymes in biosynthesis pathway and optimization of the fitness between functional modules and chassis are important for improving the production of target compounds. In this study, the taxadiene biosynthesis pathway was firstly constructed in yeast by transforming ts...

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Detalhes bibliográficos
Main Authors: Ding, Ming-zhu, Yan, Hui-fang, Li, Lin-feng, Zhai, Fang, Shang, Lu-qing, Yin, Zheng, Yuan, Ying-jin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190181/
https://ncbi.nlm.nih.gov/pubmed/25295588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109348
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