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Combining family- and population-based imputation data for association analysis of rare and common variants in large pedigrees

In the last two decades, complex traits have become the main focus of genetic studies. The hypothesis that both rare and common variants are associated with complex traits is increasingly being discussed. Family-based association studies using relatively large pedigrees are suitable for both rare an...

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Main Authors: Saad, Mohamad, Wijsman, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190076/
https://ncbi.nlm.nih.gov/pubmed/25132070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21844
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