Holoenzyme Structures of Endothelial Nitric Oxide Synthase – an Allosteric Role for Calmodulin in Pivoting the FMN Domain for Electron Transfer*

While the three-dimensional structures of heme- and flavin-binding domains of the NOS isoforms have been determined, the structures of the holoenzymes remained elusive. Application of electron cryo-microscopy and structural modeling of the bovine endothelial nitric oxide synthase (eNOS) holoenzyme p...

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Hlavní autoři: Volkmann, Niels, Martásek, Pavel, Roman, Linda J., Xu, Xiao-Ping, Page, Christopher, Swift, Mark, Hanein, Dorit, Masters, Bettie Sue
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189982/
https://ncbi.nlm.nih.gov/pubmed/25175399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2014.08.006
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