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Comparison of 2 synthetically generated recombinant prions

Prion is a protein-conformation-based infectious agent causing fatal neurodegenerative diseases in humans and animals. Our previous studies revealed that in the presence of cofactors, infectious prions can be synthetically generated in vitro with bacterially expressed recombinant prion protein (PrP)...

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Detalles Bibliográficos
Main Authors: Zhang, Yi, Wang, Fei, Wang, Xinhe, Zhang, Zhihong, Xu, Yuanyuan, Yu, Guohua, Yuan, Chonggang, Ma, Jiyan
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189893/
https://ncbi.nlm.nih.gov/pubmed/24721728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.28669
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