Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling

BACKGROUND: Pancreatic cancer is a leading cause of cancer-related deaths in the world with a 5-year survival rate of less than 6%. Currently, there is no successful therapeutic strategy for advanced pancreatic cancer, and new effective strategies are urgently needed. Recently, an arginine deprivati...

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Detalhes bibliográficos
Main Authors: Liu, Jiangbo, Ma, Jiguang, Wu, Zheng, Li, Wei, Zhang, Dong, Han, Liang, Wang, Fengfei, Reindl, Katie M, Wu, Erxi, Ma, Qingyong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189535/
https://ncbi.nlm.nih.gov/pubmed/25240403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-686
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