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Immunohistochemical Assessment of O(6)-Methylguanine-DNA Methyltransferase (MGMT) and Its Relationship with p53 Expression in Endometrial Cancers

O(6)-Methylguanine-DNA methyltransferase (MGMT) is a DNA repair protein, the loss of MGMT expression was commonly known due to hypermethylation of CpG islands in its promoter region. Overexpression of p53 protein may be associated with downregulated MGMT expression in brain tumors. The aims of this...

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Autor principal: Lee, Kyung Eun
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Cancer Prevention 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189440/
https://ncbi.nlm.nih.gov/pubmed/25337565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2013.18.4.351
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