Low-Frequency NNRTI-Resistant HIV-1 Variants and Relationship to Mutational Load in Antiretroviral-Naïve Subjects

Low-frequency HIV variants possessing resistance mutations against non‑nucleoside reverse transcriptase inhibitors (NNRTI), especially at HIV reverse transcriptase (RT) amino acid (aa) positions K103 and Y181, have been shown to adversely affect treatment response. Therapeutic failure correlates wit...

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Autors principals: Gupta, Shaili, Lataillade, Max, Kyriakides, Tassos C., Chiarella, Jennifer, St. John, Elizabeth P., Webb, Suzin, Moreno, Elizabeth A., Simen, Birgitte B., Kozal, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189030/
https://ncbi.nlm.nih.gov/pubmed/25256391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6093428
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