Low-Frequency NNRTI-Resistant HIV-1 Variants and Relationship to Mutational Load in Antiretroviral-Naïve Subjects

Low-frequency HIV variants possessing resistance mutations against non‑nucleoside reverse transcriptase inhibitors (NNRTI), especially at HIV reverse transcriptase (RT) amino acid (aa) positions K103 and Y181, have been shown to adversely affect treatment response. Therapeutic failure correlates wit...

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Huvudupphovsmän: Gupta, Shaili, Lataillade, Max, Kyriakides, Tassos C., Chiarella, Jennifer, St. John, Elizabeth P., Webb, Suzin, Moreno, Elizabeth A., Simen, Birgitte B., Kozal, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189030/
https://ncbi.nlm.nih.gov/pubmed/25256391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6093428
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