Low-Abundance HIV Drug-Resistant Viral Variants in Treatment-Experienced Persons Correlate with Historical Antiretroviral Use

BACKGROUND: It is largely unknown how frequently low-abundance HIV drug-resistant variants at levels under limit of detection of conventional genotyping (<20% of quasi-species) are present in antiretroviral-experienced persons experiencing virologic failure. Further, the clinical implications of...

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Hlavní autoři: Le, Thuy, Chiarella, Jennifer, Simen, Birgitte B., Hanczaruk, Bozena, Egholm, Michael, Landry, Marie L., Dieckhaus, Kevin, Rosen, Marc I., Kozal, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698118/
https://ncbi.nlm.nih.gov/pubmed/19562031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006079
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