Salvinorin A Regulates Dopamine Transporter Function Via A Kappa Opioid Receptor and ERK1/2-Dependent Mechanism

Salvinorin A (SalA), a selective κ-opioid receptor (KOR) agonist, produces dysphoria and pro-depressant like effects. These actions have been attributed to inhibition of striatal dopamine release. The dopamine transporter (DAT) regulates dopamine transmission via uptake of released neurotransmitter....

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Main Authors: Kivell, Bronwyn, Uzelac, Zeljko, Sundaramurthy, Santhanalakshmi, Rajamanickam, Jeyaganesh, Ewald, Amy, Chefer, Vladimir, Jaligam, Vanaja, Bolan, Elizabeth, Simonson, Bridget, Annamalai, Balasubramaniam, Mannangatti, Padmanabhan, Prisinzano, Thomas, Gomes, Ivone, Devi, Lakshmi A., Jayanthi, Lankupalle D., Sitte, Harald H., Ramamoorthy, Sammanda, Shippenberg, Toni S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188751/
https://ncbi.nlm.nih.gov/pubmed/25107591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.07.016
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