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Tyrosine Phosphorylation of the Human Serotonin Transporter: A Role in the Transporter Stability and Function

The serotonin (5-HT) transporter (SERT) regulates serotoninergic neurotransmission by clearing 5-HT released into the synaptic space. Phosphorylation of SERT on serine and threonine mediates SERT regulation. Whether tyrosine phosphorylation regulates SERT is unknown. Here, we tested the hypothesis t...

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Détails bibliographiques
Auteurs principaux: Annamalai, Balasubramaniam, Mannangatti, Padmanabhan, Arapulisamy, Obulakshmi, Shippenberg, Toni S., Jayanthi, Lankupalle D., Ramamoorthy, Sammanda
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250108/
https://ncbi.nlm.nih.gov/pubmed/21992875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073171
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