Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
We sought to examine mechanisms responsible for increased vasoconstriction that occurs during development of nitroglycerin tolerance. Rabbits were treated for 3 days with nitroglycerin patches (0.4 mg/hr), and their aortic segments were studied in organ chambers. This treatment resulted in attenuate...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.5244 |
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