A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation.

Nuclear factor kappa B (NF-kappa B) plays a critical role in the regulation of a number of genes. NF-kappa B is a heterodimer of 50- and 65-kDa subunits sequestered in the cytoplasm complexed to inhibitory protein I kappa B. Following stimulation of cells, I kappa B dissociates from NF-kappa B, allo...

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Autores principales: Diaz-Meco, M T, Berra, E, Municio, M M, Sanz, L, Lozano, J, Dominguez, I, Diaz-Golpe, V, Lain de Lera, M T, Alcamí, J, Payá, C V
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC360103/
https://ncbi.nlm.nih.gov/pubmed/8336714
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