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Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli

Clustered regularly interspaced short palindromic repeats (CRISPRs) are essential components of RNA-guided adaptive immune systems that protect bacteria and archaea from viruses and plasmids. In Escherichia coli, short CRISPR-derived RNAs (crRNAs) assemble into a 405 kDa multi-subunit surveillance c...

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Hlavní autoři: Jackson, Ryan N., Golden, Sarah M., van Erp, Paul B. G., Carter, Joshua, Westra, Edze R., Brouns, Stan J. J., van der Oost, John, Terwilliger, Thomas C., Read, Randy J., Wiedenheft, Blake
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188430/
https://ncbi.nlm.nih.gov/pubmed/25103409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256328
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