Alterations of Retinal Vasculature in Cystathionine–β-Synthase Heterozygous Mice: A Model of Mild to Moderate Hyperhomocysteinemia

Mild to moderate hyperhomocysteinemia is prevalent in humans and is implicated in neurovascular diseases, including recently in certain retinal diseases. Herein, we used hyperhomocysteinemic mice deficient in the Cbs gene encoding cystathionine–β-synthase (Cbs(+/−)) to evaluate retinal vascular inte...

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Bibliographic Details
Main Authors: Tawfik, Amany, Markand, Shanu, Al-Shabrawey, Mohamed, Mayo, Jamie N., Reynolds, Jason, Bearden, Shawn E., Ganapathy, Vadivel, Smith, Sylvia B.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2014
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Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188277/
https://ncbi.nlm.nih.gov/pubmed/25016930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.05.018
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