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Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia

Homocysteine is an amino acid required for the metabolism of methionine. Excess homocysteine is implicated in cardiovascular and neurological disease and new data suggest a role in various retinopathies. Mice lacking cystathionine-beta-synthase (cbs(−/−)) have an excess of retinal homocysteine and d...

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Bibliographic Details
Main Authors: Yu, Minzhong, Sturgill-Short, Gwen, Ganapathy, Preethi, Tawfik, Amany, Peachey, Neal S., Smith, Sylvia B.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368555/
https://ncbi.nlm.nih.gov/pubmed/22197750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.12.011
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