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Opening of the Blood-Brain Barrier before Cerebral Pathology in Mild Hyperhomocysteinemia

Hyperhomocysteinemia (HHcy) is a risk factor for cognitive impairment. The purpose of this study was to determine the temporal pattern of cerebral pathology in a mouse model of mild HHcy, because understanding this time course provides the basis for understanding the mechanisms involved. C57Bl/6 mic...

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Detalhes bibliográficos
Main Authors: Rhodehouse, Bryce C., Mayo, Jamie N., Beard, Richard S., Chen, Cheng-Hung, Bearden, Shawn E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655957/
https://ncbi.nlm.nih.gov/pubmed/23696861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063951
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